| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 10th, 2010 | 24 | Yes |
Popular Name: (2S,3S,4R,5S)-5-(6-aminopurin-9-yl)-N-butyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide (2S,3S,4R,5S)-5-(6-aminopurin-9-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.32 | 0.19 | -17.1 | 5 | 10 | 0 | 148 | 336.352 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OXGR1-1-E | G Protein-coupled Receptor 80 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 17 | 0.45 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OXGR1_RAT | Q6Y1R5 | G Protein-coupled Receptor 80, Rat | 17 | 0.45 | Binding ≤ 1μM |
| OXGR1_RAT | Q6Y1R5 | G Protein-coupled Receptor 80, Rat | 17 | 0.45 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (i) signalling events |
