In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
July 24th, 2004 | 15 | Yes |
Popular Name: dibenzo[b,f][1,4]oxazepine dibenzo[b,f][1,4]oxazepine
Find On: PubMed — Wikipedia — Google
CAS Number: 257-07-8
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.48 | 0.76 | -9.36 | 0 | 2 | 0 | 26 | 195.221 | 0 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
TRPA1-2-E | Transient Receptor Potential Cation Channel Subfamily A Member 1 (cluster #2 Of 5), Eukaryotic | Eukaryotes | 308 | 0.61 | Binding ≤ 10μM |
TRPA1-4-E | Transient Receptor Potential Cation Channel Subfamily A Member 1 (cluster #4 Of 6), Eukaryotic | Eukaryotes | 0 | 0.00 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
TRPA1_HUMAN | O75762 | Transient Receptor Potential Cation Channel Subfamily A Member 1, Human | 308 | 0.61 | Binding ≤ 1μM |
TRPA1_HUMAN | O75762 | Transient Receptor Potential Cation Channel Subfamily A Member 1, Human | 308 | 0.61 | Binding ≤ 10μM |
TRPA1_HUMAN | O75762 | Transient Receptor Potential Cation Channel Subfamily A Member 1, Human | 0.3 | 0.89 | Functional ≤ 10μM |
Description | Species |
---|---|
TRP channels |