| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 23rd, 2006 | 20 | Yes |
Popular Name: 8-Aminoadenosine 8-Aminoadenosine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 3868-33-5 , [3868-33-5]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.05 | -4.73 | -17.55 | 7 | 10 | 0 | 166 | 282.26 | 2 | ↓ |
| Lo Low (pH 4.5-6) | -1.05 | -8.84 | -35.01 | 8 | 10 | 1 | 167 | 283.268 | 2 | ↓ |
| Lo Low (pH 4.5-6) | -1.05 | -4.47 | -33.46 | 8 | 10 | 1 | 167 | 283.268 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| PUBCHEM_PATENT_ID | EP0346400A1; EP0499291A1; US4383031; US4629688; US4791055; US5965106; WO1989005647A1; WO1989005648A1; WO2000029624A2 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRP78-1-E | 78 KDa Glucose-regulated Protein (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6800 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRP78_HUMAN | P11021 | 78 KDa Glucose-regulated Protein, Human | 6800 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | |
| ATF6-alpha activates chaperone genes | |
| ATF6-alpha activates chaperones | |
| IRE1alpha activates chaperones | |
| PERK regulates gene expression | |
| Platelet degranulation |
