| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 25th, 2006 | 28 | No |
Popular Name: 1,6-BIS(CYCLOHEXYLOXIMINOCARBONYLAMINO)HEXANE 1,6-BIS(CYCLOHEXYLOXIMINOCARBONY…
Find On: PubMed — Wikipedia — Google
CAS Number: 83654-05-1
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.79 | 8.43 | -20.19 | 2 | 8 | 0 | 101 | 394.516 | 11 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DGLA-1-E | Sn1-specific Diacylglycerol Lipase Alpha (cluster #1 Of 2), Eukaryotic | Eukaryotes | 60 | 0.36 | Binding ≤ 10μM |
| DGLB-1-E | Sn1-specific Diacylglycerol Lipase Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 60 | 0.36 | Binding ≤ 10μM |
| NCEH1-1-E | Neutral Cholesterol Ester Hydrolase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 10000 | 0.25 | Binding ≤ 10μM |
| Z50597-6-O | Rattus Norvegicus (cluster #6 Of 12), Other | Other | 1000 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DGLA_HUMAN | Q9Y4D2 | Sn1-specific Diacylglycerol Lipase Alpha, Human | 60 | 0.36 | Binding ≤ 1μM |
| DGLB_HUMAN | Q8NCG7 | Sn1-specific Diacylglycerol Lipase Beta, Human | 60 | 0.36 | Binding ≤ 1μM |
| NCEH1_HUMAN | Q6PIU2 | Neutral Cholesterol Ester Hydrolase 1, Human | 10000 | 0.25 | Binding ≤ 10μM |
| DGLA_HUMAN | Q9Y4D2 | Sn1-specific Diacylglycerol Lipase Alpha, Human | 60 | 0.36 | Binding ≤ 10μM |
| DGLB_HUMAN | Q8NCG7 | Sn1-specific Diacylglycerol Lipase Beta, Human | 60 | 0.36 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 1000 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Arachidonate production from DAG |
