| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 9th, 2010 | 23 | No |
Popular Name: N-[(E)-(3,4-dihydroxyphenyl)methyleneamino]naphthalene-2-carboxamide N-[(E)-(3,4-dihydroxyphenyl)meth…
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| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.31 | 4.26 | -16.92 | 3 | 5 | 0 | 82 | 306.321 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DYN1-2-E | Dynamin-1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5100 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DYN1_HUMAN | Q05193 | Dynamin-1, Human | 5100 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| EPH-ephrin mediated repulsion of cells | |
| Formation of annular gap junctions | |
| Gap junction degradation | |
| MHC class II antigen presentation | |
| Recycling pathway of L1 | |
| Retrograde neurotrophin signalling | |
| Toll Like Receptor 4 (TLR4) Cascade |
