In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
November 18th, 2010 | 31 | No |
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.24 | 8.33 | -39.86 | 1 | 8 | -1 | 117 | 416.461 | 4 | ↓ |
Mid Mid (pH 6-8) | 2.24 | 8.79 | -16.81 | 2 | 8 | 0 | 119 | 417.469 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.41 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 0.5 | 0.42 | Binding ≤ 1μM |
CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 0.5 | 0.42 | Binding ≤ 10μM |