| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 19th, 2010 | 29 | No |
Popular Name: 4-cyano-N-[2-cyclohexen-1-yl-4-(1-oxidopyridin-1-ium-3-yl)phenyl]-1H-imidazole-2-carboxamide 4-cyano-N-[2-cyclohexen-1-yl-4-(…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.04 | 9.16 | -46.84 | 1 | 7 | -1 | 105 | 384.419 | 4 | ↓ |
| Mid Mid (pH 6-8) | 2.04 | 9.61 | -26.49 | 2 | 7 | 0 | 107 | 385.427 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.43 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 1.4 | 0.43 | Binding ≤ 1μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 1.4 | 0.43 | Binding ≤ 10μM |
