| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 20th, 2010 | 30 | No |
Popular Name: 4-cyano-N-[2-cyclohexen-1-yl-4-(2,6-dioxo-4-piperidyl)phenyl]-1H-imidazole-2-carboxamide 4-cyano-N-[2-cyclohexen-1-yl-4-(…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.00 | 6.18 | -40.31 | 2 | 8 | -1 | 126 | 402.434 | 4 | ↓ |
| Mid Mid (pH 6-8) | 2.00 | 6.64 | -17.26 | 3 | 8 | 0 | 128 | 403.442 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 1 | 0.42 | Binding ≤ 1μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 1 | 0.42 | Binding ≤ 10μM |
![N-[2-cyclohexen-1-yl-4-(2,6-diketo-4-piperidyl)phenyl]-1H-imidazole-2-carboxamide](http://zinc12.docking.org/img/rings/40372.gif)
