Physical Representations
|
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
|
Ref
Reference (pH 7)
|
3.04 |
7.2 |
-11.51 |
1 |
4 |
0 |
51 |
299.713 |
1 |
↓
|
Clustered Target Annotations
| Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
|
TBB2B-2-E |
Tubulin Beta Chain (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
890 |
0.40 |
Functional ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
| Description |
Species |
|
Formation of tubulin folding intermediates by CCT/TriC |
|
|
Gap junction assembly |
|
|
Kinesins |
|
|
MHC class II antigen presentation |
|
|
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane |
|
|
Mitotic Prometaphase |
|
|
Post-chaperonin tubulin folding pathway |
|
|
Prefoldin mediated transfer of substrate to CCT/TriC |
|
|
Recruitment of NuMA to mitotic centrosomes |
|
|
Recycling pathway of L1 |
|
|
Resolution of Sister Chromatid Cohesion |
|
|
Separation of Sister Chromatids |
|
|
Translocation of GLUT4 to the plasma membrane |
|
No pre-computed analogs available. Try a structural similarity search.
