| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 3rd, 2005 | 22 | No |
Popular Name: Dl-laudanosoline hydrobromide Dl-laudanosoline hydrobromide
Find On: PubMed — Wikipedia — Google
CAS Number: 485-33-6
(R,S)-Laudanosoline; 485-33-6; C12327; Laudanosoline
DL-Laudanosoline Hydrobromide [485-33-6]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.76 | 0.76 | -51.53 | 5 | 5 | 1 | 85 | 302.35 | 2 | ↓ |
| Mid Mid (pH 6-8) | 1.76 | -0.95 | -11.29 | 4 | 5 | 0 | 84 | 301.342 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 232-234 °C(lit.) | Indofine |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DRD4-2-E | Dopamine D4 Receptor (cluster #2 Of 4), Eukaryotic | Eukaryotes | 350 | 0.41 | Binding ≤ 10μM |
| DRD2-2-E | Dopamine D2 Receptor (cluster #2 Of 24), Eukaryotic | Eukaryotes | 1900 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DRD4_HUMAN | P21917 | Dopamine D4 Receptor, Human | 350 | 0.41 | Binding ≤ 1μM |
| DRD2_HUMAN | P14416 | Dopamine D2 Receptor, Human | 1900 | 0.36 | Binding ≤ 10μM |
| DRD4_HUMAN | P21917 | Dopamine D4 Receptor, Human | 350 | 0.41 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Dopamine receptors | |
| G alpha (i) signalling events |
