| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 8th, 2011 | 19 | No |
Popular Name: (3S,4S,5S)-4-acetamido-5-amino-3-[(1R)-1-methylpropoxy]cyclohexene-1-carboxylic (3S,4S,5S)-4-acetamido-5-amino-3…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.64 | 2.63 | -68.36 | 4 | 6 | 0 | 106 | 270.329 | 5 | ↓ |
| Hi High (pH 8-9.5) | -0.64 | 2.11 | -47.6 | 3 | 6 | -1 | 104 | 269.321 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NRAM-1-V | Neuraminidase (cluster #1 Of 2), Viral | Viruses | 7 | 0.60 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NRAM_INBLE | P03474 | Neuraminidase, Inble | 2 | 0.64 | Binding ≤ 1μM |
| NRAM_I34A1 | P03468 | Neuraminidase, I34a1 | 10 | 0.59 | Binding ≤ 1μM |
| NRAM_INBLE | P03474 | Neuraminidase, Inble | 2 | 0.64 | Binding ≤ 10μM |
| NRAM_I34A1 | P03468 | Neuraminidase, I34a1 | 10 | 0.59 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Assembly of Viral Components at the Budding Site | |
| Budding | |
| Entry of Influenza Virion into Host Cell via Endocytosis | |
| Fusion of the Influenza Virion to the Host Cell Endosome | |
| Influenza Life Cycle | |
| Influenza Virus Induced Apoptosis | |
| Packaging of Eight RNA Segments | |
| Release | |
| Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticul | |
| Uncoating of the Influenza Virion | |
| Viral mRNA Translation |
