| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 22 | No |
Popular Name: Clopamide Clopamide
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.99 | 2.32 | -16.87 | 3 | 6 | 0 | 93 | 345.852 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | . | ZereneX Building Blocks |
| mechanism | Acts at the Proximal Convoluted tubule site of the nephron | IBScreen Bioactives |
| biological_use | Antihypertensive | IBScreen Bioactives |
| biological_use | Diuretic | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Inhibitor of the sodium-chloride cotransport | IBScreen Bioactives IBScreen Bioactives |
| mechanism | intereferes with the reabsorption of NaCl and thus causing an equiosmolar excretion of water along with NaCl | IBScreen Bioactives |
| mechanism | Selectively binds at the chloride binding site of the sodium chloride cotransporter in the PCT cells on the luminal side and thus | IBScreen Bioactives |
