| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 19th, 2006 | 19 | Yes |
Popular Name: DNC005040 DNC005040
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.32 | 9.79 | -51.27 | 0 | 3 | -1 | 45 | 252.293 | 4 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 3.15e-02 g/l | DrugBank-experimental |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FABP4-3-E | Fatty Acid Binding Protein Adipocyte (cluster #3 Of 3), Eukaryotic | Eukaryotes | 570 | 0.46 | Binding ≤ 10μM |
| FABP5-2-E | Fatty Acid Binding Protein Epidermal (cluster #2 Of 2), Eukaryotic | Eukaryotes | 6700 | 0.38 | Binding ≤ 10μM |
| FABPH-2-E | Fatty Acid Binding Protein Muscle (cluster #2 Of 3), Eukaryotic | Eukaryotes | 600 | 0.46 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FABP4_HUMAN | P15090 | Fatty Acid Binding Protein Adipocyte, Human | 570 | 0.46 | Binding ≤ 1μM |
| FABPH_HUMAN | P05413 | Fatty Acid Binding Protein Muscle, Human | 600 | 0.46 | Binding ≤ 1μM |
| FABP4_HUMAN | P15090 | Fatty Acid Binding Protein Adipocyte, Human | 570 | 0.46 | Binding ≤ 10μM |
| FABP5_HUMAN | Q01469 | Fatty Acid Binding Protein Epidermal, Human | 6700 | 0.38 | Binding ≤ 10μM |
| FABPH_HUMAN | P05413 | Fatty Acid Binding Protein Muscle, Human | 600 | 0.46 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |
| Transcriptional regulation of white adipocyte differentiation |
