| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 25th, 2004 | 27 | No |
Popular Name: (1S)-6,7-dimethoxy-2,2-dimethyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium (1S)-6,7-dimethoxy-2,2-dimethyl-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.99 | 4.34 | -42.49 | 0 | 5 | 1 | 36 | 372.485 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNN1-1-E | Small Conductance Calcium-activated Potassium Channel Protein 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8700 | 0.26 | Binding ≤ 10μM |
| KCNN2-1-E | Small Conductance Calcium-activated Potassium Channel Protein 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8700 | 0.26 | Binding ≤ 10μM |
| KCNN3-1-E | Small Conductance Calcium-activated Potassium Channel Protein 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8700 | 0.26 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNN1_RAT | P70606 | Small Conductance Calcium-activated Potassium Channel Protein 1, Rat | 1300 | 0.31 | Binding ≤ 10μM |
| KCNN2_RAT | P70604 | Small Conductance Calcium-activated Potassium Channel Protein 2, Rat | 1300 | 0.31 | Binding ≤ 10μM |
| KCNN3_RAT | P70605 | Small Conductance Calcium-activated Potassium Channel Protein 3, Rat | 1300 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Ca2+ activated K+ channels |
