| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2011 | 27 | Yes |
Popular Name: N-(3,5-dimethylphenyl)-5-[4-(trifluoromethoxy)phenyl]-1,2,4-thiadiazole-3-carboxamide N-(3,5-dimethylphenyl)-5-[4-(tri…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.04 | 7.39 | -10.24 | 1 | 5 | 0 | 64 | 393.39 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SCNAA-2-E | Sodium Channel Protein Type X Alpha Subunit (cluster #2 Of 2), Eukaryotic | Eukaryotes | 8 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SCNAA_MOUSE | Q6QIY3 | Sodium Channel Protein Type 10 Subunit Alpha, Mouse | 280 | 0.34 | Binding ≤ 1μM |
| SCNAA_HUMAN | Q9Y5Y9 | Sodium Channel Protein Type X Alpha Subunit, Human | 8 | 0.42 | Binding ≤ 1μM |
| SCNAA_RAT | Q62968 | Sodium Channel Protein Type X Alpha Subunit, Rat | 520 | 0.33 | Binding ≤ 1μM |
| SCNAA_MOUSE | Q6QIY3 | Sodium Channel Protein Type 10 Subunit Alpha, Mouse | 280 | 0.34 | Binding ≤ 10μM |
| SCNAA_HUMAN | Q9Y5Y9 | Sodium Channel Protein Type X Alpha Subunit, Human | 8 | 0.42 | Binding ≤ 10μM |
| SCNAA_RAT | Q62968 | Sodium Channel Protein Type X Alpha Subunit, Rat | 520 | 0.33 | Binding ≤ 10μM |
No pre-computed analogs available. Try a structural similarity search.
