| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2011 | 28 | Yes |
Popular Name: N-(3,5-dimethylphenyl)-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide N-(3,5-dimethylphenyl)-6-[4-(tri…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.83 | 7.67 | -8.43 | 1 | 5 | 0 | 64 | 387.361 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SCNAA-1-E | Sodium Channel Protein Type X Alpha Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 21 | 0.38 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SCNAA_MOUSE | Q6QIY3 | Sodium Channel Protein Type 10 Subunit Alpha, Mouse | 57 | 0.36 | Binding ≤ 1μM |
| SCNAA_HUMAN | Q9Y5Y9 | Sodium Channel Protein Type X Alpha Subunit, Human | 21 | 0.38 | Binding ≤ 1μM |
| SCNAA_RAT | Q62968 | Sodium Channel Protein Type X Alpha Subunit, Rat | 34 | 0.37 | Binding ≤ 1μM |
| SCNAA_MOUSE | Q6QIY3 | Sodium Channel Protein Type 10 Subunit Alpha, Mouse | 57 | 0.36 | Binding ≤ 10μM |
| SCNAA_HUMAN | Q9Y5Y9 | Sodium Channel Protein Type X Alpha Subunit, Human | 21 | 0.38 | Binding ≤ 10μM |
| SCNAA_RAT | Q62968 | Sodium Channel Protein Type X Alpha Subunit, Rat | 34 | 0.37 | Binding ≤ 10μM |
No pre-computed analogs available. Try a structural similarity search.
