| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2011 | 30 | No |
Popular Name: (3E)-3-[[4-[3-(dimethylamino)propoxy]-3-methyl-azulen-1-yl]methylene]-6-fluoro-indolin-2-one (3E)-3-[[4-[3-(dimethylamino)pro…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.12 | 12.42 | -52.87 | 2 | 4 | 1 | 47 | 405.493 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FLT3-1-E | Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 742 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FLT3_HUMAN | P36888 | Tyrosine-protein Kinase Receptor FLT3, Human | 742 | 0.29 | Binding ≤ 1μM |
| FLT3_HUMAN | P36888 | Tyrosine-protein Kinase Receptor FLT3, Human | 742 | 0.29 | Binding ≤ 10μM |
No pre-computed analogs available. Try a structural similarity search.
