| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 18th, 2011 | 27 | Yes |
Popular Name: (8R)-8-(1-isobutylbenzimidazol-2-yl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one (8R)-8-(1-isobutylbenzimidazol-2…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.42 | 8.2 | -16.61 | 1 | 6 | 0 | 65 | 363.417 | 3 | ↓ |
| Lo Low (pH 4.5-6) | 3.42 | 8.77 | -33.73 | 2 | 6 | 1 | 67 | 364.425 | 3 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
![7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one](http://zinc12.docking.org/img/rings/64586.gif)
![8-(1H-benzimidazol-2-yl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one](http://zinc12.docking.org/img/rings/415627.gif)