Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
2.54 |
10.97 |
-15.75 |
0 |
5 |
0 |
57 |
335.407 |
5 |
↓
|
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRM5-2-E |
Metabotropic Glutamate Receptor 5 (cluster #2 Of 5), Eukaryotic |
Eukaryotes |
1600 |
0.32 |
Binding ≤ 10μM |
ChEMBL Target Annotations
Uniprot |
Swissprot |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRM5_RAT |
P31424
|
Metabotropic Glutamate Receptor 5, Rat |
1600 |
0.32 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
Class C/3 (Metabotropic glutamate/pheromone receptors) |
|
G alpha (q) signalling events |
|
No pre-computed analogs available. Try a structural similarity search.