| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| August 22nd, 2011 | 23 | No |
Popular Name: (1aS,7E,7aS)-7-hydroxyimino-N-(p-tolyl)-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide (1aS,7E,7aS)-7-hydroxyimino-N-(p…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.32 | 5.31 | -11.2 | 2 | 5 | 0 | 71 | 308.337 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM2-1-E | Metabotropic Glutamate Receptor 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 600 | 0.38 | Binding ≤ 10μM |
| GRM3-1-E | Metabotropic Glutamate Receptor 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8900 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM2_HUMAN | Q14416 | Metabotropic Glutamate Receptor 2, Human | 600 | 0.38 | Binding ≤ 1μM |
| GRM2_HUMAN | Q14416 | Metabotropic Glutamate Receptor 2, Human | 1500 | 0.35 | Binding ≤ 10μM |
| GRM3_HUMAN | Q14832 | Metabotropic Glutamate Receptor 3, Human | 8900 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
