| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 25th, 2006 | 29 | No |
Popular Name: 4-[hydroxy-(p-tolyl)methylene]-5-(4-isopropylphenyl)-1-(2-methoxyethyl)pyrrolidine-2,3-dione 4-[hydroxy-(p-tolyl)methylene]-5…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.32 | 9.87 | -62.1 | 0 | 5 | -1 | 70 | 392.475 | 7 | ↓ |
| Mid Mid (pH 6-8) | 4.77 | 10.49 | -13.76 | 1 | 5 | 0 | 67 | 393.483 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ANXA2-1-E | Annexin A2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8000 | 0.25 | Binding ≤ 10μM |
| S10AA-1-E | Protein S100-A10 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8000 | 0.25 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ANXA2_HUMAN | P07355 | Annexin A2, Human | 8000 | 0.25 | Binding ≤ 10μM |
| S10AA_HUMAN | P60903 | Protein S100-A10, Human | 8000 | 0.25 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Dissolution of Fibrin Clot |
