| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 2nd, 2006 | 34 | No |
Popular Name: raffinose raffinose
Find On: PubMed — Wikipedia — Google
CAS Numbers: 17629-30-0 , 512-69-6 , [512-69-6]
512-69-6; 6G-alpha-D-galactosylsucrose; C00492; Gossypose; Melitose; Melitriose; Raffinose
6G-alpha-D-galactosylsucrose; Gossypose; Melitose; Melitriose; Raffinose; bmse000221
CHEBI:26521; CHEBI:49843; CHEBI:15015; CHEBI:8771
D(+)-Raffinose pentahydrate, 99+%
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -4.90 | -23 | -18.75 | 11 | 16 | 0 | 269 | 504.438 | 8 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Mp [°C] | 78 - 80.5 | Acros Organics |
| Melting_Point | 78-82? | Alfa-Aesar |
| Melting_Point | 78-82° | Alfa-Aesar |
| UniProt Database Links | ACRB_ASPCL; ACRB_ASPFC; ACRB_ASPFU; ACRB_ASPNC; ACRB_ASPOR; ACRB_ASPTN; ACRB_EMENI; ACRB_NEOFI; AGAL1_PEDPE; AGAL2_HYPJE; AGAL3_HYPJE; AGAL8_EMENI; AGALA_ASPNG; AGALC_EMENI; AGALD_EMENI; AGALG_EMENI; AGAL_ORYSJ; AGAL_SULSO; AMML_ASTMO; CTK1_YEAST; CTK2_YE | ChEBI |
| Patent Database Links | EP0806140; EP1308171; EP1310254; EP1512429; EP1516615; EP1516923; EP1537858; EP1557463; EP1561469; EP1627642; EP1647269; EP1669082; EP1792607; EP1820516; EP1825857; EP1887017; EP1911454; EP1923060; EP1944021; US2004006222; US2007184007; US2007185203; US20 | ChEBI |
| S phrase | S24/25: Avoid contact with skin and eyes. | Acros Organics |
| PUBCHEM_PATENT_ID | US4960877 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CDK1-2-E | Cyclin-dependent Kinase 1 (cluster #2 Of 4), Eukaryotic | Eukaryotes | 150 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CDK1_HUMAN | P06493 | Cyclin-dependent Kinase 1, Human | 150 | 0.28 | Binding ≤ 1μM |
| CDK1_HUMAN | P06493 | Cyclin-dependent Kinase 1, Human | 150 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | |
| APC/C:Cdc20 mediated degradation of Cyclin B | |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |
| Condensation of Prometaphase Chromosomes | |
| Condensation of Prophase Chromosomes | |
| Cyclin A/B1 associated events during G2/M transition | |
| Cyclin B2 mediated events | |
| Depolymerisation of the Nuclear Lamina | |
| E2F mediated regulation of DNA replication | |
| E2F-enabled inhibition of pre-replication complex formation | |
| ERK1 activation | |
| G0 and Early G1 | |
| G1/S-Specific Transcription | |
| G2/M DNA replication checkpoint | |
| Golgi Cisternae Pericentriolar Stack Reorganization | |
| Loss of Nlp from mitotic centrosomes | |
| Loss of proteins required for interphase microtubule organization from the ce | |
| MASTL Facilitates Mitotic Progression | |
| Nuclear Pore Complex (NPC) Disassembly | |
| Phosphorylation of Emi1 | |
| Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 com | |
| Phosphorylation of the APC/C | |
| Recruitment of mitotic centrosome proteins and complexes | |
| Recruitment of NuMA to mitotic centrosomes | |
| Regulation of APC/C activators between G1/S and early anaphase | |
| Regulation of PLK1 Activity at G2/M Transition | |
| Resolution of Sister Chromatid Cohesion |
