| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 25th, 2004 | 27 | No |
Popular Name: (4S,7R)-2-amino-4-(2-fluorophenyl)-5-keto-7-phenyl-4,6,7,8-tetrahydrochromene-3-carbonitrile (4S,7R)-2-amino-4-(2-fluoropheny…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.63 | 1.8 | -17.55 | 2 | 4 | 0 | 76 | 360.388 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EAA1-1-E | Excitatory Amino Acid Transporter 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4786 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EAA1_HUMAN | P43003 | Excitatory Amino Acid Transporter 1, Human | 4700 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | |
| Transport of inorganic cations/anions and amino acids/oligopeptides |
