| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 24th, 2006 | 20 | Yes |
Popular Name: N-[4-chloro-3-(trifluoromethyl)phenyl]pyridine-2-carboxamide N-[4-chloro-3-(trifluoromethyl)p…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.16 | 1.42 | -7.04 | 1 | 3 | 0 | 41 | 300.667 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-1-E | Metabotropic Glutamate Receptor 4 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2100 | 0.40 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 2100 | 0.40 | Binding ≤ 10μM |
| GRM4_RAT | P31423 | Metabotropic Glutamate Receptor 4, Rat | 1700 | 0.40 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
