| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 26th, 2004 | 14 | Yes |
Popular Name: N-thiazol-2-ylpicolinamide N-thiazol-2-ylpicolinamide
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.71 | 3.35 | -12.95 | 1 | 4 | 0 | 55 | 205.242 | 2 | ↓ |
| Hi High (pH 8-9.5) | 0.78 | 1.79 | -52 | 0 | 4 | -1 | 61 | 204.234 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPM1-2-E | Methionine Aminopeptidase 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 8100 | 0.51 | Binding ≤ 10μM |
| CTR4-1-E | Cationic Amino Acid Transporter 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7000 | 0.52 | Binding ≤ 10μM |
| AMPM-2-B | Methionine Aminopeptidase (cluster #2 Of 3), Bacterial | Bacteria | 5000 | 0.53 | Binding ≤ 10μM |
| AMPM1-1-F | Methionine Aminopeptidase 1 (cluster #1 Of 1), Fungal | Fungi | 7000 | 0.52 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CTR4_HUMAN | O43246 | Cationic Amino Acid Transporter 4, Human | 5000 | 0.53 | Binding ≤ 10μM |
| AMPM_ECOLI | P0AE18 | Methionine Aminopeptidase, Ecoli | 5000 | 0.53 | Binding ≤ 10μM |
| AMPM1_HUMAN | P53582 | Methionine Aminopeptidase 1, Human | 8100 | 0.51 | Binding ≤ 10μM |
| AMPM1_YEAST | Q01662 | Methionine Aminopeptidase 1, Yeast | 7000 | 0.52 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Inactivation, recovery and regulation of the phototransduction cascade |
