| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 28th, 2006 | 33 | No |
Popular Name: NTNCBhydrochloride NTNCBhydrochloride
Find On: PubMed — Wikipedia — Google
CAS Number: 486453-65-0
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.72 | 12.33 | -59.68 | 3 | 7 | 1 | 109 | 472.631 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ADA2C-1-E | Alpha-2c Adrenergic Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 100 | 0.30 | Binding ≤ 10μM |
| NPY5R-2-E | Neuropeptide Y Receptor Type 5 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 18 | 0.33 | Binding ≤ 10μM |
| DRD2-8-E | Dopamine D2 Receptor (cluster #8 Of 24), Eukaryotic | Eukaryotes | 63 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ADA2C_HUMAN | P18825 | Alpha-2c Adrenergic Receptor, Human | 100 | 0.30 | Binding ≤ 1μM |
| DRD2_HUMAN | P14416 | Dopamine D2 Receptor, Human | 63 | 0.31 | Binding ≤ 1μM |
| NPY5R_RAT | Q63634 | Neuropeptide Y Receptor Type 5, Rat | 18 | 0.33 | Binding ≤ 1μM |
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 8 | 0.34 | Binding ≤ 1μM |
| ADA2C_HUMAN | P18825 | Alpha-2c Adrenergic Receptor, Human | 100 | 0.30 | Binding ≤ 10μM |
| DRD2_HUMAN | P14416 | Dopamine D2 Receptor, Human | 63 | 0.31 | Binding ≤ 10μM |
| NPY5R_RAT | Q63634 | Neuropeptide Y Receptor Type 5, Rat | 18 | 0.33 | Binding ≤ 10μM |
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 8 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Adrenaline signalling through Alpha-2 adrenergic receptor | |
| Adrenaline,noradrenaline inhibits insulin secretion | |
| Adrenoceptors | |
| Dopamine receptors | |
| G alpha (i) signalling events | |
| G alpha (z) signalling events | |
| Peptide ligand-binding receptors |
