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Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate |
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Aflatoxin activation and detoxification |
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alpha-linolenic acid (ALA) metabolism |
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Amino acid synthesis and interconversion (transamination) |
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Androgen biosynthesis |
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Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 |
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Cell redox homeostasis |
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Cholesterol biosynthesis |
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Chorismate via Shikimate Pathway |
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Citric acid cycle (TCA cycle) |
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Cobalamin (Cbl, vitamin B12) transport and metabolism |
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Cross-presentation of particulate exogenous antigens (phagosomes) |
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CYP2E1 reactions |
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Cytosolic iron-sulfur cluster assembly |
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Detoxification of Reactive Oxygen Species |
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Eicosanoids |
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Electron transport from NADPH to Ferredoxin |
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Endogenous sterols |
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eNOS activation |
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Estrogen biosynthesis |
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|
Fatty acids |
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|
Fatty Acyl-CoA Biosynthesis |
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FMO oxidizes nucleophiles |
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|
Glucocorticoid biosynthesis |
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Glyoxylate metabolism |
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|
Heme degradation |
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Iron uptake and transport |
|
|
Linoleic acid (LA) metabolism |
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Lysine catabolism |
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|
Metabolism of folate and pterines |
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|
Methylation |
|
|
Mineralocorticoid biosynthesis |
|
|
Miscellaneous substrates |
|
|
Mtb iron assimilation by chelation |
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|
Mycothiol metabolism |
|
|
NADPH regeneration |
|
|
Nicotinate metabolism |
|
|
Nitric oxide stimulates guanylate cyclase |
|
|
Pentose phosphate pathway (hexose monophosphate shunt) |
|
|
Phagosomal maturation (early endosomal stage) |
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|
Plasmalogen biosynthesis |
|
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Pregnenolone biosynthesis |
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Purine salvage |
|
|
Pyrimidine catabolism |
|
|
Regulation of thyroid hormone activity |
|
|
Retinoid metabolism and transport |
|
|
Sphingolipid de novo biosynthesis |
|
|
Sphingolipid metabolism |
|
|
Sterols are 12-hydroxylated by CYP8B1 |
|
|
Synthesis and interconversion of nucleotide di- and triphosphates |
|
|
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) |
|
|
Synthesis of 15-eicosatetraenoic acid derivatives |
|
|
Synthesis of 5-eicosatetraenoic acids |
|
|
Synthesis of bile acids and bile salts |
|
|
Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
|
|
Synthesis of bile acids and bile salts via 27-hydroxycholesterol |
|
|
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
|
|
Synthesis of Dolichyl-phosphate |
|
|
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) |
|
|
Synthesis of Leukotrienes (LT) and Eoxins (EX) |
|
|
Synthesis of Lipoxins (LX) |
|
|
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) |
|
|
Synthesis of very long-chain fatty acyl-CoAs |
|
|
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
|
|
The canonical retinoid cycle in rods (twilight vision) |
|
|
The retinoid cycle in cones (daylight vision) |
|
|
Thyroxine biosynthesis |
|
|
Tryptophan catabolism |
|
|
Ubiquinol biosynthesis |
|
|
VEGFA-VEGFR2 Pathway |
|
|
VEGFR2 mediated vascular permeability |
|
|
Vitamin D (calciferol) metabolism |
|
|
Vitamins |
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|
Xenobiotics |
|
