UCSF

ZINC08215755

Substance Information

In ZINC since Heavy atoms Benign functionality
July 4th, 2006 31 No

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -4.55 -1.2 -374.02 4 18 -4 290 503.15 8
Mid Mid (pH 6-8) -4.55 -2.36 -236.97 5 18 -3 287 504.158 8

Vendor Notes

Note Type Comments Provided By
UniProt Database Links 8ODP_HUMAN; 8ODP_MOUSE; 8ODP_RAT; ADOK_MYCTA; COFC_METJA; COFE_METJA; DCTP1_BOVIN; DCTP1_HUMAN; DCTP1_MOUSE; DCTP1_RAT; DER_THEMA; DGK1_LACAC; DGK1_LACJO; DGK2_LACAC; DGK2_LACJO; DGK_BACSU; DGTP2_ESCF3; DGTP_CITK8; DGTP_CROS8; DGTP_ECO24; DGTP_ECO27; DGTP ChEBI
PUBCHEM_PATENT_ID EP0212536A2; EP0254249A1; EP0684312A3; EP0684312B1; EP0816491A1; US4804748; US5198350; US5466585; US5480980; US5656596; US5702920; US5739290; US5869264; US5990303; WO1999064047A1 IBM Patent Data
Reactome Database Links REACT_21273; REACT_21292; REACT_21362; REACT_21416; REACT_7985; REACT_8004; REACT_8019; REACT_8029; REACT_9039; REACT_91 ChEBI
Patent Database Links WO2006005064 ChEBI

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Assembly of telomerase and telomere extension
DNA replication initiation
Minus-strand DNA synthesis
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Processive synthesis on the C-strand of the telomere
Synthesis and interconversion of nucleotide di- and triphosphates
Telomere C-strand synthesis initiation
Telomere Extension By Telomerase

Analogs ( Draw Identity 99% 90% 80% 70% )