| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 31st, 2013 | 0 | No |
Popular Name: Nitrendipine Nitrendipine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 39562-70-4 , [39562-70-4]
Bayotensin; Baypress; Bylotensin; Deiten; Nidrel
Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Nitrendipin;Nitrendipino [INN-Spanish];Nitrendipinum [INN-Latin]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.94 | 10.41 | -16.53 | 1 | 8 | 0 | 110 | 360.366 | 7 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 1.42e-02 g/l | DrugBank-approved |
| Indications | Antihypertensive | KeyOrganics Bioactives |
| biological_use | Antihypertensive agent | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Calcium antagonist | IBScreen Bioactives |
| Target | Calcium Channel | Selleck Chemicals |
| biological_use | Induces NO-release in endothelial cells | IBScreen Bioactives |
| mechanism | Potassium channel (IK Ca ) blocker | IBScreen Bioactives IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.