UCSF

ZINC08616945

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
June 27th, 2007 17 Yes

Popular Name: 2-amino-6-(3,4-dichlorophenyl)amino-pyrimidin-4-ol 2-amino-6-(3,4-dichlorophenyl)am…

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 4.56 -20.17 4 5 0 84 271.107 2 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PRIM-1-V DNA Helicase/primase Complex Protein (cluster #1 Of 1), Viral Viruses 850 0.50 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PRIM_HHV11 P10236 DNA Helicase/primase Complex Protein, Hhv11 850 0.50 Binding ≤ 1μM
PRIM_HHV11 P10236 DNA Helicase/primase Complex Protein, Hhv11 850 0.50 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.