| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 26 | No |
Popular Name: 3,6-diketo-2-(1-methylindol-3-yl)-5-phenyl-cyclohexa-1,4-diene-1,4-diolate 3,6-diketo-2-(1-methylindol-3-yl…
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| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.64 | 9.9 | -126.22 | 0 | 5 | -2 | 85 | 343.338 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| INSR-1-E | Insulin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| INSR_HUMAN | P06213 | Insulin Receptor, Human | 300 | 0.35 | Binding ≤ 1μM |
| INSR_HUMAN | P06213 | Insulin Receptor, Human | 300 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Insulin receptor recycling | |
| IRS activation | |
| SHC activation | |
| Signal attenuation | |
| Signaling by Insulin receptor |
