| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 30th, 2007 | 44 | No |
Popular Name: 1,2-dioleoylglycerol 1,2-dioleoylglycerol
Find On: PubMed — Wikipedia — Google
CAS Number: 2442-61-7
(R)-diolein; 2,3-di-(9Z)-octadecenoyl-sn-glycerol; DG(0:0/18:1(omega-9)/18:1(omega-9))
1,2-Diolein; 9-octadecenoic acid (Z)-, 1-(hydroxymethyl)-1,2-ethanediyl ester
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 10.06 | 27.02 | -8.98 | 1 | 5 | 0 | 73 | 621 | 36 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCD-2-E | Protein Kinase C Delta (cluster #2 Of 4), Eukaryotic | Eukaryotes | 7490 | 0.16 | Binding ≤ 10μM |
| KPCT-2-E | Protein Kinase C Theta (cluster #2 Of 3), Eukaryotic | Eukaryotes | 8670 | 0.16 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCD_HUMAN | Q05655 | Protein Kinase C Delta, Human | 7490 | 0.16 | Binding ≤ 10μM |
| KPCT_HUMAN | Q04759 | Protein Kinase C Theta, Human | 8670 | 0.16 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Apoptotic cleavage of cellular proteins | |
| Calmodulin induced events | |
| DAG and IP3 signaling | |
| Downstream TCR signaling | |
| Effects of PIP2 hydrolysis | |
| FCERI mediated NF-kB activation | |
| G alpha (z) signalling events | |
| HuR stabilizes mRNA | |
| Inactivation, recovery and regulation of the phototransduction cascade | |
| Interferon gamma signaling | |
| Netrin-1 signaling | |
| Role of phospholipids in phagocytosis | |
| VEGFR2 mediated cell proliferation |
