UCSF

ZINC00895149

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 28th, 2004 8 No

Popular Name: L-DITHIOTHREITOL L-DITHIOTHREITOL

Find On: PubMed — Wikipedia — Google

CAS Numbers: 12/3/3483 12:00:00 AM , 16096-97-2 , 27565-41-9 , 302912-05-6 , 3483-12-3 , 3483/12/3 , 6892-68-8 , [3483-12-3] , [6892-68-8]

Other Names:

(+/-)-threo-1,4-Dimercapto-2,3-butanediol

(R*,R*)-(+-)-1,4-Dimercapto-2,3-butanediol; (R*,R*)-(1)-1,4-Dimercaptobutane-2,3-diol; (R*,R*)-1,4-Dimercaptobutane-2,3-diol; 1,4-Dithiothreitol; 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-; 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)- (+-)-; 2,3-Butanedio

(R*,R*)-1,4-dimercapto-2,3-butanediol; 1,4-dithiothreitol; Cleland's reagent; DL-threo-1,4-Dimercapto-2,3-butanediol; DTL; DTT; Dithiotreitol; rac-Dithiothreitol

(R*,S*)-1,4-Dimercapto-2,3-butanediol; (R*,S*)-1,4-Dimercaptobutane-2,3-diol; 1,4-Dithioerythritol; 2,3-Butanediol, 1,4-dimercapto-, (2R,3S)-rel-; 2,3-Butanediol, 1,4-dimercapto-, (R*,S*)-; 2,3-Butanediol, 1,4-dimercapto-, (theta,S)-; BRN 1719756; DTE; Di

(R-(R*,R*))-1,4-Dimercaptobutane-2,3-diol; 2,3-Butanediol, 1,4-dimercapto-, (R-(R*,R*))-; 2,3-Butanediol, 1,4-dimercapto-, L-threo-; BRN 2036371; EINECS 240-263-0; L-1,4-Dithiothreitol; L-Dithiothreitol; L-Dtt; L-threo-1,4-Dimercapto-2,3-butanediol; LS-45

1,4-dimercapto-2,3-butanediol; 1,4-dimercaptobutane-2,3-diol

1,4-dimercaptobutane-2,3-diol

1,4-Dithio-DL-threitol

1,4-Dithio-DL-threitol, 99%

1,4-Dithio-dl-threitol; 1,4-Dithiothreitol; 1,4-disulfanylbutane-2,3-diol; 3483-12-3; DTT; dithiolthreitol; dithiothreitol; threo-1,4-Dimercapto-2,3-butanediol

1,4-Dithioerythritol

1,4-Dithioerythritol, 99%

1,4-dithiothreitol

1,4-Dithiothreitol; 3483-12-3; C00265; DL-threo-1,4-Dimercapto-2,3-butanediol; Dithiothreitol; threo-1,4-Dimercapto-2,3-butanediol

CHEBI:23854; CHEBI:4664; CHEBI:11174

CHEBI:42102; CHEBI:32885

Cleland's Reagent DTE

Cleland's Reagent DTE "erythro-1,4-Dimercapto-2,3-butanediol" UN3335 12352113 Warning H315-H319-H335 P261-P280-P305+P351+P338-P304+P340-P405-P501a

Cleland's Reagent DTT racemic

Cleland's Reagent DTT racemic "(+/-)-threo-1,4-Dimercapto-2,3-butanediol" "14,3376" 12352113 Warning H302-H315-H319-H335 P261-P280-P305+P351+P338-P304+P340-P405-P501a

Cleland's Reagent DTT racemic "(±)-threo-1,4-Dimercapto-2,3-butanediol" "14,3376" 12352113 Warning H302-H315-H319-H335 P261-P280-P305+P351+P338-P304+P340-P405-P501a

Cleland's Reagent DTT racemic "(±)-threo-1,4-Dimercapto-2,3-butanediol" "143,376" 12352113 Warning H302-H315-H319-H335 P261-P280-P305+P351+P338-P304+P340-P405-P501a

Dithioerythritol

Dithiothreitol

DL-1,4-Dithiothreitol

DL-Dithiothreitol

DL-Dithiothreitol [for Electrophoresis]

DL-Dithiothreitol-d10

DL-threo-1,4-Dimercapto-2,3-butanediol

DL-threo-2,3-Dihydroxy-1,4-dithiobutane

DTE, Cleland's reagent

DTT, Cleland's reagent

erythro-1,4-Dimercapto-2,3-butanediol

erythro-2,3-Dihydroxy-1,4-dithiolbutane

L-1,4-Dithiothreitol

MFCD00004877

MFCD00063750

MFCD00064305

rac-ClelandÕs Reagent

Store at 0-5°C

trans-1,4-Dimercaptobutane-2,3-diol

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.33 -1.73 -4.92 2 2 0 40 154.256 3 ↓
Hi High (pH 8-9.5) -0.33 -0.65 -96.35 2 2 -2 40 152.24 3 ↓
Hi High (pH 8-9.5) -0.33 -1.19 -42.76 2 2 -1 40 153.248 3 ↓

Vendor Notes

Note Type Comments Provided By
Boiling_Point 125-130?/12mm Alfa-Aesar
Boiling_Point 125-130°/12mm Alfa-Aesar
BP 130 / 2 TCI
UniProt Database Links 3XYN2_VIBSX; 3XYN_ALCSP; ACCA_PEA; ACCD_PEA; ADPRH_MOUSE; ADPRH_RAT; AGLB_THENE; AGTA_DICDI; ALDO1_ARATH; ALDO2_ARATH; ALLB_ECOLI; APQ13_YEAST; APR1_ARATH; APR2_ARATH; APR3_ARATH; CATLL_FASHE; CBAD1_ARTSP; CBAD2_ARTSP; CHAC1_HUMAN; CUL1_HUMAN; CUL1_MOUSE ChEBI
Melting_Point 40-43? Alfa-Aesar
Melting_Point 40-43° Alfa-Aesar
mp 42 - 44 MolMall (formerly Molecular Diversity Preservation International)
MP 43 TCI
MP 51 TCI
Melting_Point 82-84? Alfa-Aesar
Melting_Point 82-84° Alfa-Aesar
Patent Database Links EP1749533; EP1872792; US2004038934; US2004176570; US2005027009; US2006035295; US2006040943; US2006135759; US2007190069; US2008220536; WO2005110955; WO2007128983; WO2008151324 ChEBI
Notes Reagent for maintaining -SH groups in reduced state Apollo Scientific Bioactives
Patent Database Links WO2007135242 ChEBI

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Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.