In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
November 28th, 2005 | 18 | No |
Popular Name: 5-[(6-bromo-1,3-benzodioxol-5-yl)methylene]-1,3-thiazolidine-2,4-dione 5-[(6-bromo-1,3-benzodioxol-5-yl…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.11 | -3.03 | -7.36 | 1 | 5 | 0 | 68 | 328.143 | 1 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
IGF1R-1-E | Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3300 | 0.43 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
IGF1R_HUMAN | P08069 | Insulin-like Growth Factor I Receptor, Human | 3300 | 0.43 | Binding ≤ 10μM |
Description | Species |
---|---|
IRS-related events triggered by IGF1R | |
SHC-related events triggered by IGF1R | |
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) |