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Popular Name: (2S)-2-[[2-indan-5-yloxy-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenyl-propan-1-ol (2S)-2-[[2-indan-5-yloxy-9-[(4-p…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
ARF1-1-E ADP-ribosylation Factor 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 620 0.20 Binding ≤ 10μM
Z80936-1-O HEK293 (Embryonic Kidney Fibroblasts) (cluster #1 Of 4), Other Other 500 0.21 Functional ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.72 16.69 -18.72 2 7 0 85 567.693 10 ↓

Parameters Provided:

annotation.name = ARF1_HUMAN
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'ARF1\\_HUMAN' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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