UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

593089
593089
593092
593092

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Popular Name: D4476 D4476

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
KC1D-1-E Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic Eukaryotes 300 0.30 Binding ≤ 10μM
KPCD1-1-E Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic Eukaryotes 9100 0.24 Binding ≤ 10μM
MK14-1-E MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic Eukaryotes 5800 0.24 Binding ≤ 10μM
TGFR1-1-E TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic Eukaryotes 500 0.29 Binding ≤ 10μM
CSK2A-1-O Casein Kinase II Subunit Alpha (cluster #1 Of 1), Other Other 200 0.31 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 6.69 -16.04 3 7 0 103 398.422 4 ↓
Mid Mid (pH 6-8) 2.57 7.18 -42.22 4 7 1 104 399.43 4 ↓
Lo Low (pH 4.5-6) 2.57 6.91 -39.83 4 7 1 104 399.43 4 ↓

Parameters Provided:

annotation.name = CSK2A_SCHPO
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'CSK2A\\_SCHPO' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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