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Popular Name: 4-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)phenol hydrochloride 4-(1-methyl-1,2,3,6-tetrahydropy…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
DHPR-1-E Dihydropteridine Reductase (cluster #1 Of 1), Eukaryotic Eukaryotes 2800 0.56 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 5.42 -38.62 2 2 1 25 190.266 1 ↓

Parameters Provided:

annotation.name = DHPR_HUMAN
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'DHPR\\_HUMAN' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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