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DNLI1_HUMAN - DNA Ligase 1, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

DNA Ligase 1, Human (6 Compounds)

Swissprot:
DNLI1_HUMAN
Stitch:
DNLI1_HUMAN
UniProt:
P18858
ChEMBL:
CHEMBL5694
Reactome:
REACT_1998
REACT_74
REACT_228019
REACT_228145
REACT_8027
REACT_1385
REACT_2192
REACT_1128
REACT_977
PDB:
1X9N (DOCK)
LIG1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 6 5 1 0
Binding ≤ 1μM 1 1 0 0

Reactome Network (9)

Reactome ID Description Species
REACT_1998 Gap-filling DNA repair synthesis and ligation in GG-NER Homo sapiens
REACT_74 Gap-filling DNA repair synthesis and ligation in TC-NER Homo sapiens
REACT_228019 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) Homo sapiens
REACT_228145 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Homo sapiens
REACT_8027 Processive synthesis on the C-strand of the telomere Homo sapiens
REACT_1385 Processive synthesis on the lagging strand Homo sapiens
REACT_2192 Removal of DNA patch containing abasic residue Homo sapiens
REACT_1128 Resolution of AP sites via the multiple-nucleotide patch replacement pathway Homo sapiens
REACT_977 Resolution of D-loop structures through Holliday junction intermediates Homo sapiens

Clustered By Gene (0)