UCSF

Beta-glucocerebrosidase, Human (151 Compounds)

Swissprot:
GLCM_HUMAN
Stitch:
GLCM_HUMAN
UniProt:
P04062
ChEMBL:
CHEMBL2179
Reactome:
REACT_116105
PDB:
1OGS (DOCK)
1Y7V (DOCK)
2F61 (DOCK)
2J25 (DOCK)
2NSX (DOCK)
2NT0 (DOCK)
2NT1 (DOCK)
2V3D (DOCK)
2V3E (DOCK)
2V3F (DOCK)
2VT0 (DOCK)
2WCG (DOCK)
2WKL (DOCK)
2XWD (DOCK)
2XWE (DOCK)
3GXD (DOCK)
3GXF (DOCK)
3GXI (DOCK)
3GXM (DOCK)
3KE0 (DOCK)
3KEH (DOCK)
GBA

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 151 19 5 7
Binding ≤ 1μM 81 12 1 6

Reactome Network (1)

Reactome ID Description Species
REACT_116105 Glycosphingolipid metabolism Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AGAL_HUMAN P06280 CHEMBL2524 Alpha-galactosidase A, Human 1
BGAL_HUMAN P16278 CHEMBL2522 Beta-galactosidase, Human 24
CEGT_HUMAN Q16739 CHEMBL2063 Ceramide Glucosyltransferase, Human 2
GBA2_HUMAN Q9HCG7 CHEMBL3761 Beta-glucosidase, Human 39
GBA3_HUMAN Q9H227 CHEMBL3865 Beta-glucosidase Cytosolic, Human 30
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GLCM_BOVIN Q2KHZ8 CHEMBL1275219 Glucosylceramidase, Bovin 2 0 1 0
GLCM_MOUSE P17439 CHEMBL2278 Beta-glucocerebrosidase, Mouse 54 1 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
GLCM-1-E Glucosylceramidase (cluster #1 Of 2), Eukaryotic 110 12 0 0
GLCM-2-E Glucosylceramidase (cluster #2 Of 2), Eukaryotic 99 10 8 8
Uniprot Swissprot Chembl Description Number Shared
GBA2_HUMAN Q9HCG7 CHEMBL3761 Beta-glucosidase, Human 39
GBA3_HUMAN Q9H227 CHEMBL3865 Beta-glucosidase Cytosolic, Human 30
BGAL_HUMAN P16278 CHEMBL2522 Beta-galactosidase, Human 24
FUCO_HUMAN P04066 CHEMBL4176 Alpha-L-fucosidase I, Human 24
LYAG_BOVIN Q9MYM4 CHEMBL2974 Alpha-glucosidase, Bovin 9
CEGT_MOUSE O88693 CHEMBL6013 Ceramide Glucosyltransferase, Mouse 7
B5THE3_MOUSE B5THE3 CHEMBL1667666 Sucrase-isomaltase, Mouse 6
LYAG_HUMAN P10253 CHEMBL2608 Lysosomal Alpha-glucosidase, Human 6
LYAG_MOUSE P70699 CHEMBL1667668 Lysosomal Alpha-glucosidase, Mouse 5
MANBA_HUMAN O00462 CHEMBL3903 Beta-mannosidase, Human 4
GANAB_HUMAN Q14697 CHEMBL2519 Neutral Alpha-glucosidase AB, Human 3
LPH_RAT Q02401 CHEMBL3389 Lactase-glycosylceramidase, Rat 3
CEGT_HUMAN Q16739 CHEMBL2063 Ceramide Glucosyltransferase, Human 2
GDE_HUMAN P35573 CHEMBL5272 Glycogen Debranching Enzyme, Human 2
MGA_HUMAN O43451 CHEMBL2074 Maltase-glucoamylase, Human 2
SUIS_HUMAN P14410 CHEMBL2748 Sucrase-isomaltase, Human 2
AGAL_COFAR Q42656 CHEMBL5217 Alpha-galactosidase, Cofar 1
AGAL_HUMAN P06280 CHEMBL2524 Alpha-galactosidase A, Human 1
B1WC34_RAT B1WC34 CHEMBL2779 Alpha-glucosidase II Beta Subunit, Rat 1
BGAL_BOVIN Q58D55 CHEMBL3482 Beta-galactosidase, Bovin 1
BGLS_RHIRD P27034 CHEMBL4663 Beta-glucosidase, Rhird 1
D3ZAN3_RAT D3ZAN3 CHEMBL3352 Alpha-glucosidase II, Rat 1
GANC_MOUSE Q8BVW0 CHEMBL3635 Neutral Alpha-glucosidase C, Mouse 1
GDE_RABIT P35574 CHEMBL5273 Glycogen Debranching Enzyme, Rabit 1
LYAG_RAT Q6P7A9 CHEMBL3513 Acidic Alpha-glucosidase, Rat 1
P94451_GEOSE P94451 CHEMBL4412 Alpha-glucosidase, Geose 1
PYGL_HUMAN P06737 CHEMBL2568 Liver Glycogen Phosphorylase, Human 1
PYGL_RAT P09811 CHEMBL3239 Liver Glycogen Phosphorylase, Rat 1
PYGM_RABIT P00489 CHEMBL4696 Glycogen Phosphorylase, Muscle Form, Rabit 1
Q43014_PRUAV Q43014 CHEMBL4192 Beta-glucosidase, Pruav 1
Q9LGC6_ORYSJ Q9LGC6 CHEMBL5280 Alpha-glucosidase, Orysj 1
SUIS_RAT P23739 CHEMBL3114 Sucrase-isomaltase, Rat 1

Most Common Rings