UCSF

Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human (6 Compounds)

Swissprot:
GNAI3_HUMAN
Stitch:
GNAI3_HUMAN
UniProt:
P08754
ChEMBL:
CHEMBL4221
Reactome:
REACT_15333
REACT_20653
REACT_19231
REACT_19327
REACT_19333
REACT_15457
REACT_15426
PDB:
2IHB (DOCK)
2ODE (DOCK)
2V4Z (DOCK)
GNAI3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 6 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (7)

Reactome ID Description Species
REACT_15333 Adenylate cyclase inhibitory pathway Homo sapiens
REACT_20653 ADP signalling through P2Y purinoceptor 12 Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_19327 G alpha (s) signalling events Homo sapiens
REACT_19333 G alpha (z) signalling events Homo sapiens
REACT_15457 G-protein activation Homo sapiens
REACT_15426 PLC beta mediated events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5

ADP signalling through P2Y purinoceptor 12

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5

G alpha (s) signalling events

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5

G alpha (z) signalling events

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5

G-protein activation

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5
GNAO_HUMAN P09471 CHEMBL4742 Guanine Nucleotide-binding Protein G(o), Alpha Subunit 1, Human 5

PLC beta mediated events

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5
GNAO_HUMAN P09471 CHEMBL4742 Guanine Nucleotide-binding Protein G(o), Alpha Subunit 1, Human 5
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 6 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
GNAI1_HUMAN P63096 CHEMBL4741 Guanine Nucleotide-binding Protein G(i), Alpha-1 Subunit, Human 5
GNAO_HUMAN P09471 CHEMBL4742 Guanine Nucleotide-binding Protein G(o), Alpha Subunit 1, Human 5