UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

9227019
9227019
13161992
13161992
13161993
13161993

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Popular Name: FTS FTS

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
ICMT-2-E Isoprenylcysteine Carboxyl Methyltransferase (cluster #2 Of 2), Eukaryotic Eukaryotes 2800 0.31 Binding ≤ 10μM
TRPA1-4-E Transient Receptor Potential Cation Channel Subfamily A Member 1 (cluster #4 Of 6), Eukaryotic Eukaryotes 5000 0.30 Functional ≤ 10μM
Z80130-1-O EJ (Bladder Carcinoma Cells) (cluster #1 Of 2), Other Other 7500 0.29 Functional ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.26 15.85 -52.19 0 2 -1 40 357.539 10 ↓

Parameters Provided:

annotation.name = ICMT_RAT
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'ICMT\\_RAT' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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