UCSF

Purinergic Receptor P2Y1, Human (180 Compounds)

Swissprot:
P2RY1_HUMAN
Stitch:
P2RY1_HUMAN
UniProt:
P47900
ChEMBL:
CHEMBL4315
Reactome:
REACT_19140
REACT_18283
REACT_18289
PDB:
1Y36 (DOCK)
P2RY1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 180 10 2 1
Binding ≤ 1μM 149 7 1 0
Functional ≤ 10μM 234 20 14 2

Reactome Network (3)

Reactome ID Description Species
REACT_19140 ADP signalling through P2Y purinoceptor 1 Homo sapiens
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_18289 P2Y receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
GPR17_HUMAN Q13304 CHEMBL1075162 Uracil Nucleotide/cysteinyl Leukotriene Receptor, Human 1
P2RY2_HUMAN P41231 CHEMBL4398 Purinergic Receptor P2Y2, Human 20
P2RY6_HUMAN Q15077 CHEMBL4714 Pyrimidinergic Receptor P2Y6, Human 1
P2Y11_HUMAN Q96G91 CHEMBL4867 Purinergic Receptor P2Y11, Human 2

P2Y receptors

Uniprot Swissprot Chembl Description Number Shared
GPR17_HUMAN Q13304 CHEMBL1075162 Uracil Nucleotide/cysteinyl Leukotriene Receptor, Human 1
P2RY2_HUMAN P41231 CHEMBL4398 Purinergic Receptor P2Y2, Human 20
P2RY6_HUMAN Q15077 CHEMBL4714 Pyrimidinergic Receptor P2Y6, Human 1
P2Y11_HUMAN Q96G91 CHEMBL4867 Purinergic Receptor P2Y11, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
P2RY6_HUMAN Q15077 CHEMBL4714 Pyrimidinergic Receptor P2Y6, Human 2 1 2 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
P2RY1-1-E Purinergic Receptor P2Y1 (cluster #1 Of 2), Eukaryotic 151 9 2 1
P2RY1-2-E Purinergic Receptor P2Y1 (cluster #2 Of 2), Eukaryotic 31 2 0 0
Uniprot Swissprot Chembl Description Number Shared
P2RX2_RAT P49653 CHEMBL2135 P2X Purinoceptor 2, Rat 10
P2RX3_HUMAN P56373 CHEMBL2998 P2X Purinoceptor 3, Human 10
P2RX1_HUMAN P51575 CHEMBL2094 P2X Purinoceptor 1, Human 9
P2RX4_RAT P51577 CHEMBL2818 P2X Purinoceptor 4, Rat 8
P2Y12_RAT Q9EPX4 CHEMBL2188 Purinergic Receptor P2Y12, Rat 8
P2RX5_RAT P51578 CHEMBL2495 P2X Purinoceptor 5, Rat 7
P2RX6_RAT P51579 CHEMBL2122 P2X Purinoceptor 6, Rat 7
P2RX4_HUMAN Q99571 CHEMBL2104 P2X Purinoceptor 4, Human 6
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 5
P2RX1_RAT P47824 CHEMBL2530 P2X Purinoceptor 1, Rat 4
P2RY1_MELGA P49652 CHEMBL5720 P2Y Purinoceptor 1, Melga 3
P2RY1_RAT P49651 CHEMBL2497 Purinergic Receptor P2Y1, Rat 3
P2RY2_HUMAN P41231 CHEMBL4398 Purinergic Receptor P2Y2, Human 3
P2Y11_HUMAN Q96G91 CHEMBL4867 Purinergic Receptor P2Y11, Human 2
GPR17_HUMAN Q13304 CHEMBL1075162 Uracil Nucleotide/cysteinyl Leukotriene Receptor, Human 1
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 1
KAPCA_MOUSE P05132 CHEMBL4991 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse 1
KAPCB_MOUSE P68181 CHEMBL2481 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse 1
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 1
P2RX3_RAT P49654 CHEMBL4824 P2X Purinoceptor 3, Rat 1
P2RY4_RAT O35811 CHEMBL2124 Pyrimidinergic Receptor P2Y4, Rat 1
P2RY6_HUMAN Q15077 CHEMBL4714 Pyrimidinergic Receptor P2Y6, Human 1
Z50502 Z50502 CHEMBL613110 Meleagris Gallopavo 1

Most Common Rings