UCSF

Proteasome Macropain Subunit PRE2, Yeast (2 Compounds)

Swissprot:
PSB5_YEAST
Stitch:
PSB5_YEAST
UniProt:
P30656
ChEMBL:
CHEMBL4659
Reactome:
REACT_189060
REACT_189250
REACT_245912
REACT_189047
REACT_189025
REACT_83036
REACT_100522
REACT_230653
REACT_245870
PDB:
1FNT (DOCK)
1G0U (DOCK)
1G65 (DOCK)
1JD2 (DOCK)
1RYP (DOCK)
1VSY (DOCK)
1Z7Q (DOCK)
2F16 (DOCK)
2FAK (DOCK)
2GPL (DOCK)
2ZCY (DOCK)
3BDM (DOCK)
3D29 (DOCK)
3DY3 (DOCK)
3DY4 (DOCK)
3E47 (DOCK)
3GPJ (DOCK)
3GPT (DOCK)
3GPW (DOCK)
3HYE (DOCK)
3L5Q (DOCK)
3MG0 (DOCK)
3MG4 (DOCK)
3MG6 (DOCK)
3MG7 (DOCK)
3MG8 (DOCK)
3NZJ (DOCK)
3NZW (DOCK)
3NZX (DOCK)
3OEU (DOCK)
3OEV (DOCK)
3OKJ (DOCK)
3SHJ (DOCK)
3TDD (DOCK)
PRE2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (9)

Reactome ID Description Species
REACT_189060 Antigen processing: Ubiquitination & Proteasome degradation Saccharomyces cerevisiae
REACT_189250 AUF1 (hnRNP D0) destabilizes mRNA Saccharomyces cerevisiae
REACT_245912 CDK-mediated phosphorylation and removal of Cdc6 Saccharomyces cerevisiae
REACT_189047 Cross-presentation of soluble exogenous antigens (endosomes) Saccharomyces cerevisiae
REACT_189025 ER-Phagosome pathway Saccharomyces cerevisiae
REACT_83036 Orc1 removal from chromatin Saccharomyces cerevisiae
REACT_100522 Regulation of activated PAK-2p34 by proteasome mediated degradation Saccharomyces cerevisiae
REACT_230653 SCF-beta-TrCP mediated degradation of Emi1 Saccharomyces cerevisiae
REACT_245870 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Saccharomyces cerevisiae
Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

AUF1 (hnRNP D0) destabilizes mRNA

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

CDK-mediated phosphorylation and removal of Cdc6

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

Cross-presentation of soluble exogenous antigens (endosomes)

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

ER-Phagosome pathway

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

Orc1 removal from chromatin

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

Regulation of activated PAK-2p34 by proteasome mediated degradation

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

SCF-beta-TrCP mediated degradation of Emi1

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PSB5_HUMAN P28074 CHEMBL4662 Proteasome Macropain Subunit MB1, Human 45 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PSB5-1-E Proteasome Macropain Subunit PRE2 (cluster #1 Of 1), Eukaryotic 45 0 0 0
PSB5-1-F Proteasome Macropain Subunit PRE2 (cluster #1 Of 1), Fungal 2 0 0 0
Uniprot Swissprot Chembl Description Number Shared
PSB1_YEAST P23724 CHEMBL4904 Proteasome Component C5, Yeast 2