UCSF

Proteasome Subunit Beta Type-8, Human (11 Compounds)

Swissprot:
PSB8_HUMAN
Stitch:
PSB8_HUMAN
UniProt:
P28062
ChEMBL:
CHEMBL5620
Reactome:
REACT_118656
REACT_75842
REACT_6871
REACT_6761
REACT_172638
REACT_25325
REACT_6785
REACT_20549
REACT_1221
REACT_1949
REACT_111056
REACT_200766
REACT_11063
REACT_200841
REACT_111178
REACT_228111
REACT_228209
REACT_25162
REACT_1156
REACT_13464
REACT_13565
REACT_9003
REACT_6821
REACT_150471
REACT_1614
REACT_4
REACT_9453
REACT_9031
PDB:
PSMB8

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 11 0 0 1
Binding ≤ 1μM 11 0 0 1

Reactome Network (28)

Reactome ID Description Species
REACT_118656 Activation of NF-kappaB in B cells Homo sapiens
REACT_75842 Antigen processing: Ubiquitination & Proteasome degradation Homo sapiens
REACT_6871 APC/C:Cdc20 mediated degradation of Securin Homo sapiens
REACT_6761 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins Homo sapiens
REACT_172638 Asymmetric localization of PCP proteins Homo sapiens
REACT_25325 AUF1 (hnRNP D0) destabilizes mRNA Homo sapiens
REACT_6785 Autodegradation of Cdh1 by Cdh1:APC/C Homo sapiens
REACT_20549 Autodegradation of the E3 ubiquitin ligase COP1 Homo sapiens
REACT_1221 CDK-mediated phosphorylation and removal of Cdc6 Homo sapiens
REACT_1949 CDT1 association with the CDC6:ORC:origin complex Homo sapiens
REACT_111056 Cross-presentation of soluble exogenous antigens (endosomes) Homo sapiens
REACT_200766 degradation of AXIN Homo sapiens
REACT_11063 Degradation of beta-catenin by the destruction complex Homo sapiens
REACT_200841 degradation of DVL Homo sapiens
REACT_111178 ER-Phagosome pathway Homo sapiens
REACT_228111 Hedgehog ligand biogenesis Homo sapiens
REACT_228209 Hh ligand biogenesis disease Homo sapiens
REACT_25162 Interferon alpha/beta signaling Homo sapiens
REACT_1156 Orc1 removal from chromatin Homo sapiens
REACT_13464 Regulation of activated PAK-2p34 by proteasome mediated degradation Homo sapiens
REACT_13565 Regulation of ornithine decarboxylase (ODC) Homo sapiens
REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Homo sapiens
REACT_6821 SCF-beta-TrCP mediated degradation of Emi1 Homo sapiens
REACT_150471 Separation of Sister Chromatids Homo sapiens
REACT_1614 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Homo sapiens
REACT_4 Ubiquitin-dependent degradation of Cyclin D1 Homo sapiens
REACT_9453 Vif-mediated degradation of APOBEC3G Homo sapiens
REACT_9031 Vpu mediated degradation of CD4 Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PSB1_HUMAN P20618 CHEMBL4208 Proteasome Component C5, Human 1 0 0 0
PSB2_HUMAN P49721 CHEMBL3492 Proteasome Macropain Subunit, Human 7 0 0 0
PSB5_HUMAN P28074 CHEMBL4662 Proteasome Macropain Subunit MB1, Human 45 0 0 0

Clustered By Gene (0)