UCSF

Signal Transducer And Activator Of Transcription 5B, Human (3 Compounds)

Swissprot:
STA5B_HUMAN
Stitch:
STA5B_HUMAN
UniProt:
P51692
ChEMBL:
CHEMBL5817
Reactome:
REACT_17025
REACT_111133
REACT_27283
REACT_23837
REACT_115529
REACT_115697
REACT_121141
REACT_169118
REACT_111040
PDB:
STAT5B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3 0 0 0
Binding ≤ 1μM 3 0 0 0

Reactome Network (9)

Reactome ID Description Species
REACT_17025 Downstream signal transduction Homo sapiens
REACT_111133 Growth hormone receptor signaling Homo sapiens
REACT_27283 Interleukin-2 signaling Homo sapiens
REACT_23837 Interleukin-3, 5 and GM-CSF signaling Homo sapiens
REACT_115529 Interleukin-7 signaling Homo sapiens
REACT_115697 Prolactin receptor signaling Homo sapiens
REACT_121141 Signaling by FGFR1 fusion mutants Homo sapiens
REACT_169118 Signaling by Leptin Homo sapiens
REACT_111040 Signaling by SCF-KIT Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 3

Interleukin-2 signaling

Uniprot Swissprot Chembl Description Number Shared
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 1

Interleukin-3, 5 and GM-CSF signaling

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 3

Interleukin-7 signaling

Uniprot Swissprot Chembl Description Number Shared
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 1

Prolactin receptor signaling

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 3

Signaling by Leptin

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 3

Signaling by SCF-KIT

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 3

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 3
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 3
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 3
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 3
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 1