| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 4 | 1 | 0 | 0 |
| Binding ≤ 1μM | 1 | 0 | 0 | 0 |
| Functional ≤ 10μM | 7 | 0 | 1 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_172715 | Detoxification of Reactive Oxygen Species | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| TRXR1_HUMAN | Q16881 | CHEMBL1927 | Thioredoxin Reductase 1, Human | 10 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| TRXR2_PLAF7 | P61076 | CHEMBL4547 | Thioredoxin Reductase, Plaf7 | 7 | 6 | 1 | 0 |
| TRXR2_RAT | Q9Z0J5 | CHEMBL5086 | Thioredoxin Reductase 2, Mitochondrial, Rat | 1 | 0 | 1 | 0 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| TRXR1_HUMAN | Q16881 | CHEMBL1927 | Thioredoxin Reductase 1, Human | 5 | 1 | 0 | 0 |
| TRXR3_HUMAN | Q86VQ6 | CHEMBL3793 | Thioredoxin Reductase 3, Human | 3 | 1 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| TRXR1_HUMAN | Q16881 | CHEMBL1927 | Thioredoxin Reductase 1, Human | 10 |
| TRXR3_HUMAN | Q86VQ6 | CHEMBL3793 | Thioredoxin Reductase 3, Human | 9 |
| Z80224 | Z80224 | CHEMBL387 | MCF7 (Breast Carcinoma Cells) | 7 |
| Z81252 | Z81252 | CHEMBL400 | MDA-MB-231 (Breast Adenocarcinoma Cells) | 7 |
| TRXR2_PLAF7 | P61076 | CHEMBL4547 | Thioredoxin Reductase, Plaf7 | 2 |
| GSHR_HUMAN | P00390 | CHEMBL2755 | Glutathione Reductase, Human | 1 |