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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

2146774
2146774

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Popular Name: (1-Aminopropyl)phosphonic acid (1-Aminopropyl)phosphonic acid

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Vendors

And 5 More

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 3600 0.95 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.68 -1.47 -75.29 3 4 -1 91 138.083 2 ↓

Analogs

1720912
1720912

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Popular Name: (1-Aminopropyl)phosphonic acid (1-Aminopropyl)phosphonic acid

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Vendors

And 4 More

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 3600 0.95 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.68 -1.47 -75.3 3 4 -1 91 138.083 2 ↓

Analogs

1707645
1707645

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Popular Name: Leucine Phosphonic Acid Leucine Phosphonic Acid

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And 1 More

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 230 0.93 Binding ≤ 10μM
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 230 0.93 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.09 -0.07 -76.33 3 4 -1 91 166.137 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: DNC014304 DNC014304

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Vendors

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 1000 0.76 Binding ≤ 10μM
AMPN-5-E Aminopeptidase N (cluster #5 Of 5), Eukaryotic Eukaryotes 8300 0.65 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.89 0.86 -75.41 3 4 -1 91 180.164 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: DNC014304 DNC014304

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Vendors

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 1000 0.76 Binding ≤ 10μM
AMPN-5-E Aminopeptidase N (cluster #5 Of 5), Eukaryotic Eukaryotes 8300 0.65 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.89 0.86 -75.42 3 4 -1 91 180.164 5 ↓

Analogs

1656226
1656226

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Popular Name: 1-amino-2-phenylethylphosphonic acid; 6324-00-1; nsc30080 1-amino-2-phenylethylphosphonic …

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Vendors

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 420 0.69 Binding ≤ 10μM
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 420 0.69 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.24 1.46 -75.08 3 4 -1 91 200.154 3 ↓
Mid Mid (pH 6-8) 0.24 0.34 -34.31 4 4 0 88 201.162 3 ↓

Analogs

2569589
2569589
2573155
2573155
3304896
3304896

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Popular Name: (1-Amino-2-methylpropyl)phosphonic acid (1-Amino-2-methylpropyl)phosphon…

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Vendors

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 1200 0.92 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.44 -0.77 -75.75 3 4 -1 91 152.11 2 ↓

Analogs

1707644
1707644

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Popular Name: (1-Amino-2-methylpropyl)phosphonic acid (1-Amino-2-methylpropyl)phosphon…

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Vendors

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 1200 0.92 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.44 -0.76 -75.86 3 4 -1 91 152.11 2 ↓

Analogs

2047807
2047807

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Popular Name: (1-Amino-3-methylbutyl)phosphonic acid (1-Amino-3-methylbutyl)phosphoni…

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Vendors

And 2 More

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 230 0.93 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.09 -0.19 -74.67 3 4 -1 91 166.137 3 ↓

Analogs

3953934
3953934

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Popular Name: 1-amino-2-phenylethylphosphonic acid; 6324-00-1; nsc30080 1-amino-2-phenylethylphosphonic …

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Vendors

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPL-2-E Leucine Aminopeptidase (cluster #2 Of 2), Eukaryotic Eukaryotes 420 0.69 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.24 1.42 -76.97 3 4 -1 91 200.154 3 ↓

Parameters Provided:

target.name = AMPL-2-E
target.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN activity AS ac ON ci.sub_id_fk=ac.sub_id_fk INNER JOIN target AS t ON ac.target_fk=t.target_id  WHERE c.free = 1 AND t.code LIKE 'AMPL-2-E' AND t.atype_fk = 0 AND c.purchasable IN (1,2,4,5)    LIMIT 50

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