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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

4173567
4173567
4173568
4173568
38734073
38734073
537875
537875

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Popular Name: Ivabradine hydrochloride Ivabradine hydrochloride

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Vendors

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
HCN1-1-E Potassium/sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 4500 0.22 Binding ≤ 10μM
HCN2-1-E Potassium/sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 4520 0.22 Binding ≤ 10μM
HCN4-1-E Potassium/sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 4280 0.22 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 11.76 -56.09 1 7 1 62 469.602 10 ↓

Analogs

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Popular Name: ZATEBRADINE HYDROCHLORIDE ZATEBRADINE HYDROCHLORIDE

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Vendors

And 2 More

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
HCN2-1-E Potassium/sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 5450 0.22 Binding ≤ 10μM
HCN4-1-E Potassium/sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 8570 0.21 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 11.36 -53.7 1 7 1 62 457.591 11 ↓