UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: CARIPORIDE CARIPORIDE

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
SL9A1-1-E Sodium/hydrogen Exchanger 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 65 0.53 Binding ≤ 10μM
SL9A2-1-E Sodium/hydrogen Exchanger 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 26 0.56 Binding ≤ 10μM
SL9A3-1-E Sodium/hydrogen Exchanger 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 26 0.56 Binding ≤ 10μM
SL9A1-1-E Sodium/hydrogen Exchanger 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 75 0.52 Functional ≤ 10μM
SL9A2-1-E Sodium/hydrogen Exchanger 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 26 0.56 Functional ≤ 10μM
SL9A3-1-E Sodium/hydrogen Exchanger 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 26 0.56 Functional ≤ 10μM
Z50587-1-O Homo Sapiens (cluster #1 Of 9), Other Other 117 0.51 Functional ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.35 1.32 -19.12 4 6 0 116 283.353 3 ↓

Analogs

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Popular Name: N-(Diaminomethylene)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl)benzamide N-(Diaminomethylene)-2-methyl-5-…

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Vendors

And 2 More

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
SL9A1-1-E Sodium/hydrogen Exchanger 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 8 0.52 Binding ≤ 10μM
SL9A2-1-E Sodium/hydrogen Exchanger 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 8 0.52 Binding ≤ 10μM
SL9A3-1-E Sodium/hydrogen Exchanger 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 8 0.52 Binding ≤ 10μM
SL9A1-1-E Sodium/hydrogen Exchanger 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 8 0.52 Functional ≤ 10μM
SL9A2-1-E Sodium/hydrogen Exchanger 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 9200 0.32 Functional ≤ 10μM
SL9A3-1-E Sodium/hydrogen Exchanger 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 8 0.52 Functional ≤ 10μM
Z50587-1-O Homo Sapiens (cluster #1 Of 9), Other Other 32 0.48 Functional ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.37 3.65 -13.7 4 7 0 121 320.374 3 ↓

Parameters Provided:

target.name = SL9A2-1-E
target.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN activity AS ac ON ci.sub_id_fk=ac.sub_id_fk INNER JOIN target AS t ON ac.target_fk=t.target_id  WHERE c.free = 1 AND t.code LIKE 'SL9A2-1-E' AND t.atype_fk = 0 AND c.purchasable IN (1,2,4,5)    LIMIT 50

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//zinc12.docking.org/results/combination?target.name=SL9A2-1-E&target.type=B10&filter.purchasability=purchasable

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