B0BL08-1-B |
Dihydrofolate Reductase (cluster #1 Of 1), Bacterial |
Bacteria |
9 |
0.34 |
Binding ≤ 10μM
|
DYR-1-B |
Dihydrofolate Reductase (cluster #1 Of 4), Bacterial |
Bacteria |
7 |
0.35 |
Binding ≤ 10μM
|
DYR-1-B |
Dihydrofolate Reductase (cluster #1 Of 4), Bacterial |
Bacteria |
9 |
0.34 |
Binding ≤ 10μM
|
DYR1-1-B |
Dihydrofolate Reductase Type 1 (cluster #1 Of 1), Bacterial |
Bacteria |
7 |
0.35 |
Binding ≤ 10μM
|
DYR1-1-B |
Dihydrofolate Reductase Type 1 (cluster #1 Of 1), Bacterial |
Bacteria |
9 |
0.34 |
Binding ≤ 10μM
|
Q81R22-1-B |
Dihydrofolate Reductase (cluster #1 Of 1), Bacterial |
Bacteria |
15 |
0.33 |
Binding ≤ 10μM
|
TYSY-1-B |
Thymidylate Synthase (cluster #1 Of 1), Bacterial |
Bacteria |
1800 |
0.24 |
Binding ≤ 10μM
|
DYR-1-B |
Dihydrofolate Reductase (cluster #1 Of 1), Bacterial |
Bacteria |
26 |
0.32 |
Functional ≤ 10μM
|
DRTS-1-E |
Bifunctional Dihydrofolate Reductase-thymidylate Synthase (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
11 |
0.34 |
Binding ≤ 10μM
|
DRTS-1-E |
Bifunctional Dihydrofolate Reductase-thymidylate Synthase (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
33 |
0.32 |
Binding ≤ 10μM
|
DYR-1-E |
Dihydrofolate Reductase (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3 |
0.36 |
Binding ≤ 10μM |
DYR-1-E |
Dihydrofolate Reductase (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
5 |
0.35 |
Binding ≤ 10μM
|
FOLC-1-E |
Folylpoly-gamma-glutamate Synthetase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3200 |
0.23 |
Binding ≤ 10μM
|
PTR1-1-E |
Pteridine Reductase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
39 |
0.31 |
Binding ≤ 10μM
|
S19A1-1-E |
Folate Transporter 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3500 |
0.23 |
Binding ≤ 10μM
|
TYSY-1-E |
Thymidylate Synthase (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3600 |
0.23 |
Binding ≤ 10μM
|
DYR-1-F |
Dihydrofolate Reductase (cluster #1 Of 1), Fungal |
Fungi |
880 |
0.26 |
Binding ≤ 10μM
|
Z103204-2-O |
A427 (cluster #2 Of 4), Other |
Other |
5520 |
0.22 |
Functional ≤ 10μM
|
Z50266-1-O |
Enterococcus Faecium (cluster #1 Of 1), Other |
Other |
90 |
0.30 |
Functional ≤ 10μM
|
Z50362-1-O |
Lactobacillus Casei (cluster #1 Of 1), Other |
Other |
6 |
0.35 |
Functional ≤ 10μM
|
Z50425-3-O |
Plasmodium Falciparum (cluster #3 Of 22), Other |
Other |
85 |
0.30 |
Functional ≤ 10μM
|
Z50587-1-O |
Homo Sapiens (cluster #1 Of 9), Other |
Other |
6600 |
0.22 |
Functional ≤ 10μM
|
Z50594-1-O |
Mus Musculus (cluster #1 Of 9), Other |
Other |
4200 |
0.23 |
Functional ≤ 10μM
|
Z80001-1-O |
143B (cluster #1 Of 2), Other |
Other |
9 |
0.34 |
Functional ≤ 10μM
|
Z80008-1-O |
5637 (Epithelial Bladder Carcinoma Cells) (cluster #1 Of 3), Other |
Other |
16 |
0.33 |
Functional ≤ 10μM
|
Z80025-1-O |
ACHN (Renal Adenocarcinoma Cells) (cluster #1 Of 3), Other |
Other |
40 |
0.31 |
Functional ≤ 10μM
|
Z80054-1-O |
Caco-2 (Colon Adenocarcinoma Cells) (cluster #1 Of 4), Other |
Other |
1100 |
0.25 |
Functional ≤ 10μM
|
Z80063-1-O |
CCRF S-180 (cluster #1 Of 1), Other |
Other |
10 |
0.34 |
Functional ≤ 10μM
|
Z80064-1-O |
CCRF-CEM (T-cell Leukemia) (cluster #1 Of 9), Other |
Other |
8 |
0.34 |
Functional ≤ 10μM
|
Z80064-1-O |
CCRF-CEM (T-cell Leukemia) (cluster #1 Of 9), Other |
Other |
620 |
0.26 |
Functional ≤ 10μM
|
Z80099-1-O |
COLO 205 (Colon Adenocarcinoma Cells) (cluster #1 Of 3), Other |
Other |
870 |
0.26 |
Functional ≤ 10μM
|
Z80112-1-O |
DAN-G (cluster #1 Of 2), Other |
Other |
77 |
0.30 |
Functional ≤ 10μM
|
Z80125-1-O |
DU-145 (Prostate Carcinoma) (cluster #1 Of 9), Other |
Other |
45 |
0.31 |
Functional ≤ 10μM
|
Z80132-1-O |
EL4 (Thymoma Cells) (cluster #1 Of 2), Other |
Other |
1570 |
0.25 |
Functional ≤ 10μM
|
Z80156-2-O |
HL-60 (Promyeloblast Leukemia Cells) (cluster #2 Of 12), Other |
Other |
7 |
0.35 |
Functional ≤ 10μM
|
Z80156-2-O |
HL-60 (Promyeloblast Leukemia Cells) (cluster #2 Of 12), Other |
Other |
8 |
0.34 |
Functional ≤ 10μM
|
Z80166-12-O |
HT-29 (Colon Adenocarcinoma Cells) (cluster #12 Of 12), Other |
Other |
4400 |
0.23 |
Functional ≤ 10μM |
Z80171-1-O |
HuTu80 (cluster #1 Of 1), Other |
Other |
9 |
0.34 |
Functional ≤ 10μM
|
Z80186-1-O |
K562 (Erythroleukemia Cells) (cluster #1 Of 11), Other |
Other |
26 |
0.32 |
Functional ≤ 10μM
|
Z80192-1-O |
KM12 (Colon Adenocarcinoma Cells) (cluster #1 Of 4), Other |
Other |
42 |
0.31 |
Functional ≤ 10μM
|
Z80193-2-O |
L1210 (Lymphocytic Leukemia Cells) (cluster #2 Of 12), Other |
Other |
10 |
0.34 |
Functional ≤ 10μM
|
Z80214-1-O |
M14 (Melanoma Cells) (cluster #1 Of 3), Other |
Other |
32 |
0.32 |
Functional ≤ 10μM
|
Z80224-1-O |
MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other |
Other |
900 |
0.26 |
Functional ≤ 10μM
|
Z80227-1-O |
MCF7-ADR (Breast Carcinoma Cells) (cluster #1 Of 2), Other |
Other |
78 |
0.30 |
Functional ≤ 10μM
|
Z80285-2-O |
MOLT-4 (Acute T-lymphoblastic Leukemia Cells) (cluster #2 Of 4), Other |
Other |
28 |
0.32 |
Functional ≤ 10μM
|
Z80354-1-O |
OVCAR-3 (Ovarian Adenocarcinoma Cells) (cluster #1 Of 4), Other |
Other |
400 |
0.27 |
Functional ≤ 10μM
|
Z80356-1-O |
OVCAR-5 (Ovarian Adenocarcinoma Cells) (cluster #1 Of 2), Other |
Other |
980 |
0.25 |
Functional ≤ 10μM
|
Z80357-1-O |
OVCAR-8 (Ovarian Adenocarcinoma Cells) (cluster #1 Of 1), Other |
Other |
31 |
0.32 |
Functional ≤ 10μM
|
Z80362-8-O |
P388 (Lymphoma Cells) (cluster #8 Of 8), Other |
Other |
66 |
0.30 |
Functional ≤ 10μM |
Z80390-3-O |
PC-3 (Prostate Carcinoma Cells) (cluster #3 Of 10), Other |
Other |
27 |
0.32 |
Functional ≤ 10μM
|
Z80407-1-O |
R1 (cluster #1 Of 1), Other |
Other |
720 |
0.26 |
Functional ≤ 10μM
|
Z80408-1-O |
R1-CCRF-CEM (Lymphoblastic Leukemia) (cluster #1 Of 1), Other |
Other |
985 |
0.25 |
Functional ≤ 10μM
|
Z80409-1-O |
R2 (cluster #1 Of 1), Other |
Other |
216 |
0.28 |
Functional ≤ 10μM
|
Z80409-1-O |
R2 (cluster #1 Of 1), Other |
Other |
2600 |
0.24 |
Functional ≤ 10μM
|
Z80410-1-O |
R2-CCRF-CEM (Lymphoblastic Leukemia) (cluster #1 Of 1), Other |
Other |
2630 |
0.24 |
Functional ≤ 10μM
|
Z80411-1-O |
R30dm-CCRF-CEM (Lymphoblastic Leukemia) (cluster #1 Of 1), Other |
Other |
18 |
0.33 |
Functional ≤ 10μM
|
Z80414-1-O |
Raji (B-lymphoblastic Cells) (cluster #1 Of 3), Other |
Other |
40 |
0.31 |
Functional ≤ 10μM
|
Z80433-1-O |
RPMI-8226 (Multiple Myeloma Cells) (cluster #1 Of 3), Other |
Other |
33 |
0.32 |
Functional ≤ 10μM
|
Z80443-1-O |
S180 (Sarcoma Cells) (cluster #1 Of 1), Other |
Other |
5 |
0.35 |
Functional ≤ 10μM
|
Z80455-1-O |
SCC-15 (cluster #1 Of 1), Other |
Other |
580 |
0.26 |
Functional ≤ 10μM
|
Z80457-1-O |
SCC-25 (cluster #1 Of 1), Other |
Other |
8 |
0.34 |
Functional ≤ 10μM
|
Z80459-1-O |
SCC-7 (cluster #1 Of 1), Other |
Other |
6 |
0.35 |
Functional ≤ 10μM
|
Z80468-1-O |
SF-295 (Glioblastoma Cells) (cluster #1 Of 2), Other |
Other |
36 |
0.32 |
Functional ≤ 10μM
|
Z80488-2-O |
SK-MEL-5 (Melanoma Cells) (cluster #2 Of 3), Other |
Other |
87 |
0.30 |
Functional ≤ 10μM
|
Z80526-1-O |
SW480 (Colon Adenocarcinoma Cells) (cluster #1 Of 6), Other |
Other |
15 |
0.33 |
Functional ≤ 10μM
|
Z80560-1-O |
U-251 (Glioma Cells) (cluster #1 Of 3), Other |
Other |
63 |
0.31 |
Functional ≤ 10μM
|
Z80563-1-O |
U-373 MG ( Glioblastoma Cells) (cluster #1 Of 1), Other |
Other |
12 |
0.34 |
Functional ≤ 10μM
|
Z80565-1-O |
U-87 MG (Glioblastoma Cells) (cluster #1 Of 2), Other |
Other |
22 |
0.32 |
Functional ≤ 10μM
|
Z80568-1-O |
UACC-257 (Melanoma Cells) (cluster #1 Of 1), Other |
Other |
790 |
0.26 |
Functional ≤ 10μM
|
Z80570-3-O |
UACC-62 (Melanoma Cells) (cluster #3 Of 3), Other |
Other |
28 |
0.32 |
Functional ≤ 10μM
|
Z80575-1-O |
UO-31 (Renal Carcinoma Cells) (cluster #1 Of 3), Other |
Other |
191 |
0.29 |
Functional ≤ 10μM
|
Z80583-1-O |
Vero (Kidney Cells) (cluster #1 Of 7), Other |
Other |
9 |
0.34 |
Functional ≤ 10μM
|
Z80640-1-O |
786-0 (Renal Carcinoma Cells) (cluster #1 Of 1), Other |
Other |
33 |
0.32 |
Functional ≤ 10μM
|
Z80657-1-O |
A253 Cell Line (cluster #1 Of 1), Other |
Other |
3000 |
0.23 |
Functional ≤ 10μM
|
Z80682-11-O |
A549 (Lung Carcinoma Cells) (cluster #11 Of 11), Other |
Other |
5 |
0.35 |
Functional ≤ 10μM |
Z80682-11-O |
A549 (Lung Carcinoma Cells) (cluster #11 Of 11), Other |
Other |
37 |
0.32 |
Functional ≤ 10μM |
Z80711-1-O |
NCI/ADR-RES (Breast Carcinoma Cells) (cluster #1 Of 2), Other |
Other |
78 |
0.30 |
Functional ≤ 10μM
|
Z80752-1-O |
Carcinoma Cell Line (cluster #1 Of 1), Other |
Other |
15 |
0.33 |
Functional ≤ 10μM
|
Z80789-1-O |
Colon 38 (cluster #1 Of 1), Other |
Other |
66 |
0.30 |
Functional ≤ 10μM
|
Z80815-1-O |
D54 Cell Line (cluster #1 Of 1), Other |
Other |
16 |
0.33 |
Functional ≤ 10μM
|
Z80830-1-O |
Ehrlich (Ehrlich Ascites Carcinoma Cells) (cluster #1 Of 1), Other |
Other |
13 |
0.33 |
Functional ≤ 10μM
|
Z80847-1-O |
FaDu (Pharyngeal Carcinoma Cells) (cluster #1 Of 3), Other |
Other |
31 |
0.32 |
Functional ≤ 10μM
|
Z80874-1-O |
CEM (T-cell Leukemia) (cluster #1 Of 7), Other |
Other |
9740 |
0.21 |
Functional ≤ 10μM
|
Z80890-1-O |
H350.3 (MTX-resistant Reuber Hepatoma Cells) (cluster #1 Of 1), Other |
Other |
906 |
0.26 |
Functional ≤ 10μM
|
Z80893-1-O |
H35 (Reuber Hepatoma Cells) (cluster #1 Of 1), Other |
Other |
10 |
0.34 |
Functional ≤ 10μM
|
Z80920-1-O |
HCC 2998 (Colon Adenocarcinoma Cells) (cluster #1 Of 2), Other |
Other |
110 |
0.30 |
Functional ≤ 10μM
|
Z80928-3-O |
HCT-116 (Colon Carcinoma Cells) (cluster #3 Of 9), Other |
Other |
30 |
0.32 |
Functional ≤ 10μM
|
Z81017-1-O |
WiDr (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other |
Other |
25 |
0.32 |
Functional ≤ 10μM
|
Z81024-1-O |
NCI-H460 (Non-small Cell Lung Carcinoma) (cluster #1 Of 8), Other |
Other |
10 |
0.34 |
Functional ≤ 10μM
|
Z81054-1-O |
SF-268 (Glioblastoma Cells) (cluster #1 Of 3), Other |
Other |
52 |
0.31 |
Functional ≤ 10μM
|
Z81065-1-O |
IGROV-1 (Ovarian Adenocarcinoma Cells) (cluster #1 Of 3), Other |
Other |
65 |
0.30 |
Functional ≤ 10μM
|
Z81115-2-O |
KB (Squamous Cell Carcinoma) (cluster #2 Of 6), Other |
Other |
6 |
0.35 |
Functional ≤ 10μM
|
Z81115-2-O |
KB (Squamous Cell Carcinoma) (cluster #2 Of 6), Other |
Other |
6 |
0.35 |
Functional ≤ 10μM |
Z81184-1-O |
LOX IMVI (Melanoma Cells) (cluster #1 Of 5), Other |
Other |
26 |
0.32 |
Functional ≤ 10μM
|
Z81247-1-O |
HeLa (Cervical Adenocarcinoma Cells) (cluster #1 Of 9), Other |
Other |
100 |
0.30 |
Functional ≤ 10μM
|
Z81281-1-O |
NCI-H23 (Non-small Cell Lung Carcinoma Cells) (cluster #1 Of 5), Other |
Other |
43 |
0.31 |
Functional ≤ 10μM
|
Z81283-1-O |
NCI-H522 (Non-small Cell Lung Carcinoma Cells) (cluster #1 Of 2), Other |
Other |
450 |
0.27 |
Functional ≤ 10μM
|
Z81322-1-O |
SF-539 (Glioblastoma Cells) (cluster #1 Of 2), Other |
Other |
35 |
0.32 |
Functional ≤ 10μM
|
Z81325-1-O |
SR (Leukemia Cells) (cluster #1 Of 2), Other |
Other |
33 |
0.32 |
Functional ≤ 10μM
|
Z81331-1-O |
SW-620 (Colon Adenocarcinoma Cells) (cluster #1 Of 6), Other |
Other |
33 |
0.32 |
Functional ≤ 10μM
|
Z81335-1-O |
HCT-15 (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other |
Other |
30 |
0.32 |
Functional ≤ 10μM
|
Z80253-1-O |
MEF (Embryonic Fibroblast Cells) (cluster #1 Of 2), Other |
Other |
120 |
0.29 |
ADME/T ≤ 10μM
|
Z80409-1-O |
R2 (cluster #1 Of 1), Other |
Other |
216 |
0.28 |
ADME/T ≤ 10μM |